Bioanalytics Workshop
Date and time
Location
Beth Israel Deaconess Medical Center
X-Ray Crystallography Core, Research North 99 Brookline Avenue Boston, MA 02215Description
Learn about measuring binding affinity, protein stability and aggregation from the experts.
- Hear scientific talks by local researchers
- Discuss how the latest technologies, Microscale Thermophoresis and nanoDSF, help to advance your research
- Generate data from your own samples
- Network with your peers from Academia and Industry
Thursday, April 6
9:00 am Welcome from Gabriel Birrane, PhD (BIDMC, X-Ray Crystallography Core)
9:10 am Engineering biomolecular nanostructures for enhanced enzyme catalysis: the need for quantitative substrate binding measurements (Dr. Ian Wheeldon, Assistant Professor of Chemical & Environmental Engineering, University of California, Riverside)
9:40 am Cytochrome c oxidase assembly: Characterization of Cu chaperones (Dr. Iulian Trasnea, Postdoctoral Researcher, Department of Biology, University of Pennsylvania)
10:10 am Coffee break
10:30 am Identification of Nrf1 as an ER membrane cholesterol sensor guarding homeostasis. (Dr. Scott Widenmaier, Research Fellow, Department of Genetics and Complex Diseases, Harvard School of Public Health)
11:00 am Biologics Stability Screening Has Never Been Faster, Easier & More Fun (Charles Heffern, PhD, NanoTemper)
11:30 am New Applications to Take Your Research to the Next Level (Dinorah Leyva, PhD, NanoTemper)
12:00 pm Lunch available
1:00 pm Breakout Workshops
- Sample preparation overview for Microscale Thermophoresis and nanoDSF for new users (Nicole Eckart, PhD, NanoTemper)
- Experimental work on user samples
5:30 pm Bill's Bar (5 Lansdowne St, Boston)
Friday, April 7
9:00 am Refreshments networking reception
9:30 am Experimental work on user samples
12:00 pm Lunch available
1:00 pm Experimental work on user samples
3:30 pm End of day
Who should attend?
Scientists working in:
- Protein purification
- X-ray or protein crystallography
- Cryo EM
- Drug development
- Formulation development
- Process development
Or struggling with:
- Small molecules
- Therapeutic proteins
- Sensitive membrane proteins
I want to bring my own samples. What do I need to do?
For experimental work on binding affinity using Microscale Thermophoresis, fill out this form.
For experimental work on protein stability and aggregation using nanoDSF, fill out this form.
For questions, please contact Gabriel Birrane, PhD (gbirrane@bidmc.harvard.edu, 617-667-0025)
Organized by
X-ray Crystallography Core
The X-ray Crystallography Facility was recently established as a core to serve the needs of investigators in the BIDMC and Harvard Medical School community interested in using structural biology as a tool in their research.